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| 18:45 | FT | Aston Villa | 0 : 2 | Middlesbrough | Finished |
| 18:45 | AET | Bournemouth | 1 : 0 | Brighton | After ET |
| 18:45 | FT | Brentford | 1 : 3 | Norwich City | Finished |
| 18:45 | FT | Bristol City | 2 : 0 | Stoke City | Finished |
| 18:45 | Pen | Burnley | 5 : 7 | Leeds United | Pen: 3-5 |
| 18:45 | FT | Crystal Palace | 1 : 0 | Huddersfield Town | Finished |
| 18:45 | FT | Leicester City | 2 : 0 | Liverpool | Finished |
| 18:45 | AET | Wolverhampton | 1 : 0 | Bristol Rovers | After ET |
| 19:00 | FT | Reading | 0 : 2 | Swansea City | Finished |
| 18:00 | FT | Valencia CF | 5 : 0 | Malaga CF | H2H | Finished |
| 18:00 | 21' | Athletic Bilbao | 0 : 0 | Atletico Madrid | H2H | 1st Half |
| 18:00 | 21' | CD Leganes | 0 : 0 | Girona FC | H2H | 1st Half |
| 18:00 | Pen | Sporting Gijon | 2 : 4 | Numancia | Pen: 1-3 |
| 18:00 | 21' | Cordoba CF | 1 : 1 | CD Tenerife | 1st Half |
| 18:00 | 22' | SD Formentera | 0 : 0 | UD Logrones | 1st Half |
| 18:15 | 6' | Gimnastica Segoviana | 0 : 0 | SD Ponferradina | 1st Half |
| 19:00 | - | Hercules CF | - : - | Elche CF |
| 19:30 | - | Real Murcia | - : - | UE Olot |
| 18:45 | FT | Bologna | 1 : 1 | Inter Milan | H2H | Finished |
| 16:30 | FT | Borussia Monchengladbach | 2 : 0 | VfB Stuttgart | H2H | Finished |
| 18:30 | FT | FC Augsbourg | 1 : 0 | RB Leipzig | H2H | Finished |
| 18:30 | FT | FC Schalke 04 | 0 : 3 | Bayern Munich | H2H | Finished |
| 18:30 | FT | VfL Wolfsbourg | 1 : 1 | Werder Bremen | H2H | Finished |
| 16:30 | 90' | 1. FC Koln | 0 : 1 | Eintracht Frankfurt | H2H | 2nd Half |
| 14:00 | FT | ASKO Oedt | 2 : 0 | SC Austria Lustenau | Finished |
| 17:00 | Pst | Austria Klagenfurt | 0 : 0 | Kapfenberger SV | Postp. |
| 17:00 | FT | Gleisdorf | 1 : 2 | Wolfsberger AC | Finished |
| 17:00 | FT | SC Neusiedl | 0 : 1 | SV Ried | Finished |
| 17:00 | FT | Union St. Florian | 1 : 0 | SC Weiz | Finished |
| 17:30 | FT | SKU Amstetten | 0 : 1 | Wacker Innsbruck | Finished |
| 17:30 | Pen | SV Horn | 6 : 7 | TSV Hartberg | Pen: 3-4 |
| 16:00 | FT | USK Anif | 1 : 2 | Sturm Graz | Finished |
| 16:30 | FT | VST Volkermarkt | 0 : 3 | Austria Wien | Finished |
| 17:00 | Pst | Bad Gleichenberg | 0 : 0 | Admira Wacker | Postp. |
| 17:00 | Pst | SC Parndorf | 0 : 0 | SV Mattersburg | Postp. |
| 17:00 | 62' | Union Gurten | 1 : 1 | SCR Altach | 2nd Half |
| 18:00 | FT | KV Kortrijk | 5 : 3 | RE Durbuy | Finished |
| 18:30 | FT | Royal Antwerp | 2 : 0 | Lierse | Finished |
| 18:30 | AET | Sint-Truiden | 4 : 2 | Oud-Heverlee Leuven2 | After ET |
| 18:00 | 22' | Cercle Brugge | 0 : 1 | KRC Genk | 1st Half |
| 18:00 | 21' | KV Mechelen | 1 : 0 | Bocholt | 1st Half |
| 18:00 | 21' | KV Oostende | 0 : 0 | Union Saint-Gilloise | 1st Half |
| 18:00 | 22' | Lommel United | 1 : 2 | Waasland-Beveren | 1st Half |
| 18:00 | 21' | Mouscron-Peruwelz | 0 : 0 | Tubize | 1st Half |
| 18:00 | 21' | RFC Liege | 0 : 0 | Zulte Waregem | 1st Half |
| 18:30 | - | KAS Eupen | - : - | Rupel Boom |
| 18:45 | - | Westerlo | - : - | Anderlecht |
| 14:00 | Pen | Rudar Prijedor | 6 : 5 | Tekstilac Derventa | Pen: 5-4 |
| 14:00 | FT | Azot Vitkovici | 1 : 2 | Sloboda Tuzla | Finished |
| 14:00 | FT | Bratsvo Gracanica | 6 : 1 | Sutjeska Foca | Finished |
| 14:00 | FT | FK Vitez | 3 : 9 | Borac Banja Luka | Finished |
| 14:00 | FT | FK Zvijezda 09 | 2 : 0 | Bosna Visoko | Finished |
| 14:00 | FT | HNK Grude | 0 : 4 | Krupa na Vrbasu | Finished |
| 14:00 | FT | Leotar Trebinje | 4 : 0 | Kozara Gradiska | Finished |
| 14:00 | FT | Ljubic Prnjavor | 0 : 6 | NK Vitez | Finished |
| 14:00 | FT | Metalleghe-BSI | 0 : 1 | Zeljeznicar | Finished |
| 14:00 | Pen | Mladost Doboj Kakanj | 4 : 3 | Sarajevo | Pen: 4-3 |
| 14:00 | FT | Radnik Bijeljina | 0 : 1 | Siroki Brijeg | Finished |
| 14:00 | Pen | Slaven Zivinice | 6 : 7 | NK Celik Zenica | Pen: 4-5 |
| 14:00 | FT | Sloga Doboj | 1 : 0 | Zrinjski Mostar | Finished |
| 14:00 | Pen | Svatovac Polijice | 6 : 5 | Slavija Sarajevo | Pen: 5-4 |
| 14:00 | Pen | TOSK Tesanj | 7 : 6 | Gosk Gabela | Pen: 5-4 |
| 14:00 | FT | Velez Mostar | 1 : 3 | Olimpic sarajevo | Finished |
| 13:00 | FT | FC Sevlievo | 0 : 2 | Beroe Stara Zagora | Finished |
| 13:00 | FT | Neftohimik | 1 : 2 | Tsarsko selo | Finished |
| 13:00 | FT | Nesebar | 1 : 4 | CSKA Sofia | Finished |
| 13:00 | FT | Sokol-Markovo | 1 : 4 | Dunav Ruse | Finished |
| 16:00 | AET | Botev Galabovo | 0 : 1 | Levski Sofia | After ET |
| 13:00 | AET | Botev Vratsa | 3 : 1 | Pirin Blagoevgrad | After ET |
| 13:00 | FT | Chernomorets Burgas | 0 : 2 | Slavia Sofia | Finished |
| 13:00 | FT | Lokomotiv Sofia | 2 : 1 | FC Vereya | Finished |
| 13:00 | FT | Montana | 2 : 1 | Cherno More Varna | Finished |
| 13:00 | FT | Strumska slava | 2 : 1 | FC Sozopol | Finished |
| 16:00 | FT | Litex Lovech | 1 : 0 | Vitosha Bistritsa | Finished |
| 13:30 | FT | Slavonija Pozega | 1 : 2 | Zadar | Finished |
| 13:30 | FT | Bedem Ivankovo | 0 : 3 | Lokomotiva zagreb | Finished |
| 13:30 | FT | Borac Imbriovec | 0 : 6 | Dinamo Zagreb | Finished |
| 13:30 | FT | Croatia Zmijavci | 0 : 1 | Slaven Belupo | Finished |
| 13:30 | FT | Dakovo | 0 : 4 | NK Istra 1961 | Finished |
| 13:30 | Pst | HNK Gorica | 0 : 0 | NK Gosk Dubrovnik | Postp. |
| 13:30 | FT | Nedelisce | 0 : 6 | Inter Zapresic | Finished |
| 13:30 | FT | Nehaj Senj | 0 : 6 | Osijek | Finished |
| 13:30 | FT | NK Sesvete | 3 : 0 | Rnk Split | Finished |
| 13:30 | FT | NK Vrbovec | 1 : 3 | Rijeka | Finished |
| 13:30 | FT | Oriolik | 0 : 3 | Hajduk Split | Finished |
| 13:30 | Pst | Rudes | 0 : 0 | Vinogradar | Postp. |
| 13:30 | FT | Zagora Unesic | 0 : 3 | Sibenik | Finished |
| 16:00 | Pst | Varteks Varazdin | 0 : 0 | HNK Cibalia | Postp. |
| 16:00 | FT | Omonia Nicosia | 5 : 2 | AEK Larnaca | H2H | Finished |
| 14:00 | FT | FC MAS Taborsko | 3 : 4 | Teplice | Finished |
| 16:00 | Pen | Bohemians 1905 | 5 : 6 | Graffin Vlasim | Pen: 3-4 |
| 14:00 | AET | FK Hodonin | 0 : 4 | Slovan Liberec | After ET |
| 14:00 | FT | Hfk Olomouc | 1 : 8 | Hradec Kralove | Finished |
| 14:00 | FT | Jiskra Rymarov | 3 : 2 | Dukla Prague | Finished |
| 14:00 | FT | Sokol Zivanice | 0 : 8 | Sigma Olomouc | Finished |
| 15:00 | FT | Jablonec | 2 : 1 | Viktoria Zizkov | Finished |
| 15:00 | FT | Mlada Boleslav | 3 : 0 | Pribram | Finished |
| 15:00 | FT | Vysocina Jihlava | 1 : 0 | Banik Sokolov | Finished |
| 16:15 | FT | Znojmo | 0 : 1 | Sparta Prague | Finished |
| 16:30 | FT | Slavia Prague | 5 : 1 | Trinec | Finished |
| 14:30 | FT | VB 1968 | 0 : 3 | Jammerbugt FC | Finished |
| 17:00 | FT | Kjellerup IF | 0 : 6 | Silkeborg IF | Finished |
| 14:30 | FT | Greve | 0 : 7 | FC Midtjylland | Finished |
| 14:30 | FT | Hedensted IF | 1 : 3 | Lyngby BK | Finished |
| 14:30 | FT | Middelfart | 0 : 2 | AaB Aalborg | Finished |
| 14:30 | FT | Naestved BK | 1 : 3 | HB Koge | Finished |
| 14:30 | FT | Otterup | 0 : 2 | Randers FC | Finished |
| 16:15 | FT | Skive IK | 0 : 3 | FC Copenhagen | Finished |
| 17:00 | 65' | B 73 Slagelse | 1 : 3 | Hobro IK | 2nd Half |
| 17:00 | 68' | Holbaek BI | 1 : 0 | AC Horsens | 2nd Half |
| 17:00 | 64' | Hvidovre IF | 0 : 0 | FC Helsingor | 2nd Half |
| 18:45 | FT | Wigan Athletic | 1 : 0 | Northampton Town | H2H | Finished |
| 18:30 | FT | Accrington Stanley | 3 : 2 | Middlesbrough U23 | Finished |
| 18:45 | FT | Walsall | 3 : 1 | West Brom U23 | Finished |
| 14:00 | FT | Laanemaa Haapsalu | 1 : 7 | FCI Tallinn | Finished |
| 15:00 | FT | Flora Tallinn | 2 : 0 | FC Elva | Finished |
| 14:00 | FT | FC Levadia Tallinn | 7 : 0 | K-Jarve JK Jarve | Finished |
| 14:00 | FT | Tulevik Viljandi | 3 : 0 | FC Maardu | Finished |
| 15:00 | Pen | Nomme Kalju FC | 6 : 5 | Paide LM III | Pen: 5-4 |
| 17:00 | 65' | Rumori Calcio | 0 : 2 | FC Kuressaare | 2nd Half |
| 17:30 | 45' | Flora Tallinn II | 0 : 0 | Flora Tallinn II | 1st Half |
| 15:30 | FT | Haka Valkeakoski | 2 : 2 | OPS | H2H | Finished |
| 19:00 | FT | Ajaccio | 3 : 0 | Valenciennes | H2H | Finished |
| 19:00 | FT | Chateauroux | 0 : 2 | Clermont Foot 63 | H2H | Finished |
| 19:00 | FT | Nancy | 2 : 1 | Bourg-Peronnas | H2H | Finished |
| 19:00 | FT | Reims | 5 : 0 | Gazelec Ajaccio | H2H | Finished |
| 16:30 | FT | FC Ingolstadt | 2 : 2 | MSV Duisbourg | H2H | Finished |
| 16:30 | FT | FC Kaiserslautern | 0 : 2 | FC Erzgebirge Aue | H2H | Finished |
| 16:30 | FT | Kieler SV Holstein | 0 : 1 | St Pauli | H2H | Finished |
| 16:30 | FT | SV Sandhausen | 1 : 0 | 1. FC Union Berlin | H2H | Finished |
| 16:30 | FT | 1. FC Heidenheim | 2 : 2 | SV Darmstadt | H2H | Finished |
| 16:30 | 90' | Eintracht Braunschweig | 3 : 0 | SpVgg Greuther Furth | H2H | 2nd Half |
| 16:30 | 90' | SC Fortuna Dusseldorf | 1 : 0 | SSV Jahn Regensburg | H2H | 2nd Half |
| 16:30 | 90' | SG Dynamo Dresden | 0 : 2 | DSC Arminia Bielefeld | H2H | 2nd Half |
| 17:00 | FT | 1. FC Magdeburg | 1 : 0 | SC Paderborn | H2H | Finished |
| 17:00 | FT | FC Hansa Rostock | 1 : 1 | FSV Zwickau | H2H | Finished |
| 17:00 | FT | SG Sonnenhof | 1 : 0 | Karlsruher SC | H2H | Finished |
| 17:00 | FT | VFL Sportfreunde Lotte | 0 : 1 | SV Wehen | H2H | Finished |
| 17:00 | FT | Werder Bremen II | 1 : 2 | Hallescher FC | H2H | Finished |
| 16:30 | FT | SV Meppen | 1 : 0 | VfL Osnabruck | H2H | Finished |
| 17:00 | 64' | Chemnitzer FC | 1 : 2 | SC Fortuna Koln | H2H | 2nd Half |
| 17:00 | 63' | FC RW Erfurt | 0 : 2 | SpVgg Unterhaching | H2H | 2nd Half |
| 17:00 | 64' | FC Wurzburger Kickers | 1 : 2 | FC Carl Zeiss Jena | H2H | 2nd Half |
| 17:00 | 67' | SC Preussen Munster | 0 : 0 | VfR Aalen | H2H | 2nd Half |
| 13:00 | FT | Aiginiakos | 0 : 1 | Apollon Kalamarias | Finished |
| 13:00 | FT | Panserraikos | 2 : 0 | Ergotelis | Finished |
| 15:15 | FT | Xanthi | 2 : 0 | Panaitolikos | Finished |
| 17:30 | FT | Olympiakos | 2 : 1 | Asteras Tripolis | Finished |
| 13:00 | FT | Atromitos | 1 : 0 | AOK Kerkyra | Finished |
| 13:00 | FT | Platanias | 1 : 0 | Apollon Smyrni | Finished |
| 15:15 | FT | Panachaiki | 1 : 0 | Anagennisi Karditsas | Finished |
| 15:15 | FT | PAOK Salonika | 2 : 1 | Levadiakos | Finished |
| 17:30 | HT | AEK Athens | 0 : 0 | Lamia FC | Half Time |
| 17:30 | HT | Panathinaikos | 1 : 0 | AEL Larissa | Half Time |
| 18:30 | FT | Ascoli Picchio | 0 : 1 | Frosinone | H2H | Finished |
| 18:30 | FT | Cittadella | 4 : 0 | Cesena | H2H | Finished |
| 18:30 | FT | Pescara | 2 : 2 | Virtus Entella | H2H | Finished |
| 18:30 | FT | Pro Vercelli | 1 : 1 | Salernitana | H2H | Finished |
| 18:30 | FT | Spezia Calcio | 1 : 0 | Novara Calcio | H2H | Finished |
| 18:30 | Ssp | Ternana Calcio | 0 : 0 | Brescia Calcio | H2H | Suspended |
| 16:00 | FT | FK Liepaja | 4 : 1 | Rigas FS | Finished |
| 16:00 | ET | Riga | 2 : 1 | Spartaks Jurmala | Extra Time |
| 15:00 | FT | Kauno Zalgiris | 0 : 1 | Atlantas Klaipeda | H2H | Finished |
| 17:00 | FT | FK Trakai | 0 : 0 | FK Lietava | H2H | Finished |
| 14:00 | FT | Utenis Utena | 1 : 2 | Zalgiris Vilnius | H2H | Finished |
| 15:00 | FT | Stumbras Kaunas | 1 : 3 | Suduva Marijampole | H2H | Finished |
| 14:00 | FT | Tauras Taurag? | 5 : 1 | Zalgiris Vilnius B | H2H | Finished |
| 15:00 | FT | VV Zwaluwen | 2 : 3 | Den Bosch | Finished |
| 16:30 | FT | RKC Waalwijk | 1 : 0 | Sparta Rotterdam | Finished |
| 17:45 | FT | Barendrecht | 1 : 3 | Go Ahead Eagles | Finished |
| 17:45 | FT | FC Emmen | 1 : 3 | NEC Nijmegen | Finished |
| 17:45 | FT | FC Oss | 0 : 2 | Almere City FC | Finished |
| 17:45 | FT | GVVV | 1 : 0 | FC Dordrecht | Finished |
| 17:45 | FT | Helmond Sport | 1 : 5 | Cambuur | Finished |
| 17:45 | Pen | Kozakken Boys | 5 : 4 | De Graafschap | Pen: 4-3 |
| 17:45 | FT | Noordwijk | 0 : 1 | Fortuna Sittard | Finished |
| 17:45 | FT | Quick Boys | 1 : 3 | FC Volendam | Finished |
| 17:45 | FT | Rijnsburgse Boys | 0 : 2 | Heracles Almelo | Finished |
| 17:45 | FT | SC Genemuiden | 1 : 3 | De Treffers | Finished |
| 17:45 | FT | Sparta Nijkerk | 0 : 1 | FC Eindhoven | Finished |
| 18:45 | FT | MVV Maastricht | 2 : 3 | AZ Alkmaar | Finished |
| 15:00 | Pen | Swift | 5 : 3 | Vitesse Arnhem | Pen: 5-3 |
| 16:30 | FT | SVV Scheveningen | 1 : 5 | Ajax | Finished |
| 17:45 | 36' | Achilles 29 | 1 : 2 | NAC | 1st Half |
| 17:45 | 37' | AGOVV Apeldoorn | 0 : 0 | Willem II | 1st Half |
| 17:45 | 36' | ASV De Dijk | 0 : 1 | HHC Hardenberg | 1st Half |
| 17:45 | 37' | Excelsior | 0 : 2 | Heerenveen | 1st Half |
| 17:45 | 36' | Staphorst | 0 : 0 | Koninklijke HFC | 1st Half |
| 17:00 | FT | Bodo/Glimt | 1 : 0 | Tromsdalen UIL | H2H | Finished |
| 18:15 | 7' | Valerenga | 0 : 0 | Sarpsborg 08 | 1st Half |
| 15:45 | Pen | Bytovia Bytow | 5 : 4 | Pogon Szczecin | Pen: 5-4 |
| 18:45 | AET | Podbeskidzie Bielsko Biala | 1 : 2 | Arka Gdynia | After ET |
| 15:45 | AET | Gornik Zabrze | 3 : 2 | Sandecja Nowy Sacz | After ET |
| 14:00 | FT | Rozwoj Katowice | 0 : 2 | Legionovia Legionowo | H2H | Finished |
| 16:00 | FT | Arouca | 2 : 0 | Sporting Lisbon B | H2H | Finished |
| 13:30 | FT | Academy Pandev | 2 : 0 | Pelister Bitola | H2H | Finished |
| 13:30 | FT | Pobeda Prilep | 2 : 4 | Rabotnicki | H2H | Finished |
| 13:30 | FT | Shkupi Skopje | 1 : 0 | FK Skopje | H2H | Finished |
| 15:30 | FT | FC Voluntari | 1 : 0 | ACS Poli Timisoara | H2H | Finished |
| 18:00 | FT | Sepsi | 2 : 3 | CS Universitatea Craiova | H2H | Finished |
| 15:30 | FT | FC Botosani | 3 : 3 | CSMS Iasi | H2H | Finished |
| 18:00 | Pst | Dinamo Bucharest | 0 : 0 | Concordia Chiajna | H2H | Postp. |
| 09:00 | FT | Luch Energiya | 2 : 0 | Anzhi | H2H | Finished |
| 12:00 | FT | FK Tambov | 1 : 0 | Arsenal Tula | H2H | Finished |
| 12:00 | FT | Gazovik Orenburg | 0 : 2 | Rubin Kazan | H2H | Finished |
| 12:00 | FT | Shinnik Yaroslavl | 3 : 0 | FC Ural | H2H | Finished |
| 12:00 | FT | Tom Tomsk | 2 : 1 | FC Krasnodar | H2H | Finished |
| 14:00 | AET | Avangard Kursk | 1 : 0 | CSKA Moscow | After ET |
| 15:00 | FT | Volgar Astrakhan | 0 : 2 | Rostov | H2H | Finished |
| 15:30 | Pen | Spartak Naltchik | 4 : 2 | Dynamo Moscow | H2H | Pen: 4-2 |
| 16:00 | FT | Kuban Krasnodar | 0 : 2 | Spartak Moscow | H2H | Finished |
| 05:00 | FT | FC Sakhalin | 0 : 1 | Dynamo Barnaul | H2H | Finished |
| 06:00 | FT | Smena Komsomolsk | 0 : 1 | Irtysh Omsk | H2H | Finished |
| 09:00 | FT | Zenit Irkutsk | 1 : 4 | FC Chita | H2H | Finished |
| 19:15 | FT | Sporting Lisbon | 0 : 0 | Maritimo | H2H | Finished |
| 15:00 | FT | Leixoes | 1 : 0 | Pacos Ferreira | H2H | Finished |
| 18:45 | FT | Hibernian | 3 : 2 | Livingston | Finished |
| 18:45 | AET | Partick Thistle | 1 : 3 | Glasgow Rangers | After ET |
| 15:00 | FT | Borac Cacak | 0 : 2 | Crvena Zvezda | H2H | Finished |
| 16:30 | FT | MFK Ruzomberok | 1 : 0 | MSK Zilina | H2H | Finished |
| 17:00 | FT | Podbrezova | 2 : 0 | Tatran Presov | H2H | Finished |
| 18:30 | FT | Slovan Bratislava | 3 : 1 | Zemplin Michalovce | H2H | Finished |
| 16:30 | FT | As Trencin | 2 : 1 | FC Nitra | H2H | Finished |
| 17:00 | 66' | Dunajska Streda | 0 : 0 | FK Senica | H2H | 2nd Half |
| 17:00 | 60' | Spartak Trnava | 1 : 0 | Zlate Moravce | H2H | 2nd Half |
| 13:30 | Pen | Buducnost Dobanovci | 7 : 5 | Vozdovac | Pen: 4-2 |
| 13:30 | FT | Dinamo Pancevo | 1 : 2 | Vojvodina | Finished |
| 13:30 | Pen | FK Macva Sabac | 4 : 2 | Backa Palanka | Pen: 4-2 |
| 13:30 | Pen | Indjija | 5 : 4 | Radnik Surdulica | Pen: 5-4 |
| 13:30 | FT | Javor Ivanjica | 2 : 0 | FK Sindjelic | Finished |
| 13:30 | FT | Polet Lipljan | 1 : 8 | Spartak Subotica | Finished |
| 13:30 | FT | Radnicki Novi Beograd | 0 : 1 | Mladost Lucani | Finished |
| 13:30 | Pen | Radnicki Pirot | 7 : 6 | Novi Pazar | Pen: 6-5 |
| 13:30 | Pen | Zlatibor Cajetina | 7 : 6 | Radnicki | Pen: 7-6 |
| 17:00 | 64' | FK Metalac | 1 : 1 | Proleter Novi Sad | 2nd Half |
| 14:00 | FT | Jadran Dekani | 0 : 7 | NK Aluminij | Finished |
| 18:00 | FT | NK Radomlje | 1 : 6 | Olimpija Ljubljana | Finished |
| 11:00 | FT | NK Drava Ptuj | 0 : 3 | NK Celje | Finished |
| 13:00 | FT | NS Mura | 3 : 1 | NK Domzale | Finished |
| 14:00 | FT | NK Sampion Celje | 0 : 3 | ND Gorica | Finished |
| 14:00 | Pst | NK Zarica Kranj | 0 : 0 | Nafta 1903 | H2H | Postp. |
| 17:00 | FT | Elfsborg | 2 : 2 | Djurgardens IF | H2H | Finished |
| 17:00 | FT | IFK Norrkoping | 4 : 1 | BK Hacken | H2H | Finished |
| 17:00 | 66' | Halmstads BK | 0 : 1 | Kalmar FF | H2H | 2nd Half |
| 17:00 | 61' | Hammarby IF | 2 : 1 | IFK Goteborg | H2H | 2nd Half |
| 17:00 | 67' | Jonkopings Sodra | 2 : 0 | Sirius | H2H | 2nd Half |
| 17:00 | 65' | Ostersunds FK | 1 : 1 | Malmo FF | H2H | 2nd Half |
| 17:00 | FT | Mallbackens IF (W) | 1 : 2 | Orebro (W) | Finished |
| 17:00 | 45' | Lidkoping FK (W) | 0 : 0 | Hovas Billdal (W) | 1st Half |
| 18:00 | 21' | Lausanne-Sport | 0 : 1 | FC Zurich | H2H | 1st Half |
| 18:00 | 21' | St. Gallen | 1 : 0 | Basel | H2H | 1st Half |
| 18:00 | 22' | Young Boys | 0 : 0 | Luzern | H2H | 1st Half |
| 18:00 | 21' | Neuchatel Xamax | 0 : 1 | Servette | H2H | 1st Half |
| 18:00 | 23' | Rapperswil-Jona | 0 : 0 | Wil | H2H | 1st Half |
| 10:00 | FT | Anadolu Bagcilar | 0 : 1 | Anadolu Selcuksport | Finished |
| 10:00 | AET | Tokatspor | 0 : 1 | Kahramanmarasspor | After ET |
| 10:45 | Pen | Sanliurfaspor | 5 : 3 | Pazarspor | Pen: 4-2 |
| 11:30 | FT | Diyarbekirspor | 0 : 1 | Istanbulspor | Finished |
| 12:30 | FT | Bandirmaspor | 0 : 1 | Corum Belediyespor | Finished |
| 12:30 | AET | Bodrumspor | 2 : 3 | Gaziantep BB | After ET |
| 12:30 | FT | Kirklarelispor | 1 : 3 | Nigde Belediyespor | Finished |
| 12:30 | FT | Menemen Belediyespor | 4 : 2 | Darica Genclerbirligi | Finished |
| 12:30 | Pen | Muglaspor | 3 : 4 | Etimesgut Belediyespor | Pen: 2-3 |
| 13:00 | FT | Belediye Vanspor | 0 : 1 | Kayserispor | Finished |
| 14:00 | Pen | Balikesirspor | 6 : 7 | Kars 36 Spor | Pen: 5-6 |
| 16:00 | AET | Kemerspor | 0 : 1 | Sivas Belediyespor | After ET |
| 16:00 | FT | Mersin Idman Yurdu | 3 : 5 | Orhangazispor | Finished |
| 10:00 | FT | Inegolspor | 0 : 2 | Yeni Malatyaspor | Finished |
| 11:00 | Pen | Duzyurtspor | 8 : 9 | Gumushanespor | Pen: 4-5 |
| 11:30 | FT | Batman Petrolspor | 3 : 1 | Goztepe | Finished |
| 12:00 | FT | Denizlispor | 1 : 0 | Duzcespor | Finished |
| 12:00 | FT | Erzin Belediyespor | 1 : 2 | Karagumruk | Finished |
| 12:00 | FT | Hacettepe SK | 1 : 2 | Yeni Altindag | Finished |
| 12:00 | FT | Hatayspor | 1 : 0 | Ergene Velime Spor | Finished |
| 12:00 | FT | Kastamonuspor | 1 : 3 | Ofspor | Finished |
| 12:00 | FT | Keciorengucu | 3 : 1 | Silivrispor | Finished |
| 12:00 | AET | Sancaktepespor | 2 : 4 | Elazigspor | After ET |
| 12:30 | FT | Bergama Belediye | 0 : 2 | Sariyer | Finished |
| 12:30 | Pen | Kocaeli BirlikSpor | 5 : 7 | Edirnespor Genclik | Pen: 3-5 |
| 12:30 | FT | Tuzlaspor | 1 : 0 | Zonguldak Komurspor | Finished |
| 12:30 | FT | Yesil Bursa | 3 : 1 | Karsiyaka | Finished |
| 13:00 | FT | Giresunspor | 3 : 1 | Cizre Sport | Finished |
| 14:00 | Pen | Altay Izmir | 5 : 4 | BB Erzurumspor | Pen: 5-4 |
| 15:00 | FT | Altinordu | 1 : 0 | Sultanbeyli Belediyespor | Finished |
| 15:00 | FT | Bucaspor | 2 : 0 | Pendikspor | Finished |
| 16:00 | FT | Adana Demirspor | 3 : 0 | Bayrampasaspor | Finished |
| 16:00 | FT | Gaziantepspor | 0 : 3 | Tire 1922 | Finished |
| 16:00 | FT | Manisaspor | 4 : 1 | Arsinspor | Finished |
| 16:00 | ET | Samsunspor | 3 : 3 | Ankara Demirspor | Extra Time |
| 17:30 | HT | Fethiyespor | 0 : 0 | Nazilli Belediyespor | Half Time |
| 18:30 | FT | Airbus UK Broughton | 2 : 0 | Flint Town | H2H | Finished |
| 18:30 | FT | Rhyl FC | 0 : 1 | Ruthin Town FC | H2H | Finished |
| 13:00 | AET | Ahrobiznes Volochysk | 1 : 2 | Veres Rivne | After ET |
| 13:00 | FT | Kolos Kovalivka | 1 : 2 | Illichivets Mariupol | Finished |
| 13:00 | AET | Tavriya Simferopol | 3 : 2 | Zirka Kirovohrad | After ET |
| 13:00 | Pen | Zhemchuzhyna Odesa | 2 : 5 | Stal Dniprodzerzhynsk | Pen: 1-4 |
| 14:00 | FT | Helios Kharkiv | 1 : 2 | Desna Chernihiv | Finished |
| 14:30 | Pen | Inhulets Petrove | 5 : 6 | Arsenal Kiev | Pen: 5-6 |
| 15:00 | FT | Avanhard Kramatorsk | 0 : 2 | Vorskla Poltava | Finished |
| 16:00 | FT | SCC Demnya | 1 : 2 | FC Lviv | Finished |
| 16:00 | FT | SK Dnipro-1 | 1 : 0 | Hirnyk-Sport Komsomolsk | Finished |
| 15:00 | FT | Belarus (W) | 1 : 0 | Albania (W) | H2H | Finished |
| 15:00 | FT | Romania (W) | 0 : 1 | Italy (W) | H2H | Finished |
| 15:55 | FT | Norway (W) | 6 : 1 | Slovakia (W) | H2H | Finished |
| 16:00 | FT | Croatia (W) | 0 : 2 | Sweden (W) | H2H | Finished |
| 16:00 | FT | Czech Republic (W) | 0 : 1 | Germany (W) | H2H | Finished |
| 16:00 | FT | Hungary (W) | 1 : 6 | Denmark (W) | H2H | Finished |
| 17:00 | FT | Switzerland (W) | 2 : 1 | Poland (W) | H2H | Finished |
| 18:00 | FT | England (W) | 6 : 0 | Russia (W) | H2H | Finished |
| 18:00 | FT | Serbia (W) | 0 : 4 | Austria (W) | H2H | Finished |
| 18:15 | FT | Belgium (W) | 12 : 0 | Moldova (W) | H2H | Finished |
| 18:30 | FT | Northern Ireland (W) | 0 : 2 | Ireland (W) | H2H | Finished |
| 17:30 | 45' | Al-Ittihad Bahrain | 0 : 1 | Manama | H2H | 1st Half |
| 11:00 | Pst | Farashganj | 0 : 0 | Brothers Union | H2H | Postp. |
| 13:15 | Pst | Team BJMC | 0 : 0 | Sheikh Moni Arambagh | H2H | Postp. |
| 11:30 | Pst | Abahani Chittagong | 0 : 0 | Saif SC | H2H | Postp. |
| 12:00 | Pst | Sheikh Jamal | 0 : 0 | Abahani | H2H | Postp. |
| 11:35 | FT | Shanghai Shenhua | 0 : 0 | Shandong Luneng | H2H | Finished |
| 08:00 | FT | Persija | 1 : 0 | Perseru Serui | H2H | Finished |
| 08:00 | FT | Bhayangkara FC | 2 : 1 | Pusamania Borneo FC | H2H | Finished |
| 11:30 | FT | Mitra Kukar | 0 : 3 | Arema FC | H2H | Finished |
| 10:00 | FT | Cerezo Osaka | 1 : 0 | Nagoya Grampus Eight | Finished |
| 10:00 | FT | Gamba Osaka | 2 : 3 | Kashiwa Reysol | Finished |
| 10:00 | FT | Kawasaki Frontale | 4 : 1 | Shimizu S-Pulse | Finished |
| 10:00 | FT | Matsumoto Yamaga | 0 : 2 | Vissel Kobe | Finished |
| 10:00 | FT | Parceiro Nagano | 0 : 1 | Jubilo Iwata | Finished |
| 10:00 | FT | Tsukuba University | 0 : 2 | Omiya Ardija | Finished |
| 10:00 | FT | Urawa Red Diamonds | 2 : 4 | Kashima Antlers | Finished |
| 10:00 | AET | Yokohama F Marinos | 3 : 2 | Sanfrecce Hiroshima | After ET |
| 16:30 | FT | Al Wihdat | 2 : 0 | Al Jazeera | Finished |
| 12:00 | FT | Akzhayik Uralsk | 1 : 0 | FC Atyrau | H2H | Finished |
| 14:00 | FT | Kairat Almaty | 5 : 1 | Ordabasy | H2H | Finished |
| 10:00 | FT | Gwangju FC | 1 : 4 | FC Seoul | H2H | Finished |
| 10:00 | FT | Jeonbuk Motors | 1 : 2 | Sangju Sangmu | H2H | Finished |
| 10:00 | FT | Jeonnam Dragons | 0 : 0 | Incheon United | H2H | Finished |
| 10:30 | FT | Pohang Steelers | 5 : 2 | Gangwon FC | H2H | Finished |
| 10:30 | FT | Suwon Bluewings | 2 : 3 | Jeju United | H2H | Finished |
| 10:30 | FT | Ulsan Hyundai | 3 : 2 | Daegu FC | H2H | Finished |
| 13:00 | FT | Johor Darul FC | 3 : 0 | Kelantan | H2H | Finished |
| 13:00 | FT | Kedah | 1 : 3 | Felda United | H2H | Finished |
| 13:00 | FT | Melaka United | 3 : 1 | Perak | H2H | Finished |
| 13:00 | FT | Pulau Pinang | 0 : 2 | PBDKT T-Team | H2H | Finished |
| 08:45 | FT | MISC | 1 : 2 | Terengganu | H2H | Finished |
| 13:00 | FT | PDRM | 5 : 3 | Kuantan FA | H2H | Finished |
| 13:00 | FT | PKNP FC | 3 : 1 | Negeri Sembilan | H2H | Finished |
| 13:00 | FT | UiTM FC | 1 : 2 | Kuala Lumpur | H2H | Finished |
| 12:50 | FT | Dhamk | 1 : 2 | Al Shoalah | H2H | Finished |
| 15:40 | FT | Al Mojzel | 1 : 2 | Al Qaisoma | H2H | Finished |
| 12:55 | FT | Al Taee Hail | 1 : 2 | Al Wehda | H2H | Finished |
| 16:05 | FT | Jeddah | 1 : 1 | Al Khaleej | H2H | Finished |
| 11:30 | FT | Home United | 1 : 1 | Albirex Niigata FC | H2H | Finished |
| 12:15 | FT | Brunei DPMM | 1 : 4 | Hougang United | H2H | Finished |
| 11:30 | FT | Tampines Rovers | 1 : 1 | Warriors | H2H | Finished |
| 11:30 | FT | Young Lions | 0 : 1 | Balestier Khalsa | H2H | Finished |
| 10:45 | FT | Port FC | 1 : 3 | Chonburi FC | H2H | Finished |
| 10:45 | FT | Samut Prakan FC | 1 : 3 | Suphanburi FC | H2H | Finished |
| 11:00 | FT | Chiangrai United | 6 : 0 | Sukhothai FC | H2H | Finished |
| 11:00 | FT | Nakhon Ratchasima | 1 : 1 | Navy FC | H2H | Finished |
| 12:00 | FT | Sisaket FC | 0 : 3 | Ratchaburi FC | H2H | Finished |
| 12:00 | FT | Thai Honda FC | 0 : 0 | Pattaya United | H2H | Finished |
| 12:00 | FT | Ubon UMT United | 1 : 1 | BEC Tero Sasana | H2H | Finished |
| 13:00 | FT | Buriram United | 1 : 0 | Bangkok Glass | H2H | Finished |
| 13:00 | FT | MuangThong | 4 : 0 | Bangkok United | H2H | Finished |
| 11:00 | FT | Nong Bua Pitchaya | 0 : 0 | Kasetsart FC | H2H | Finished |
| 11:00 | FT | Rayong FC | 5 : 0 | Chiangmai FC | H2H | Finished |
| 11:00 | FT | Songkhla United | 3 : 3 | Army United | H2H | Finished |
| 12:00 | FT | Air Force Central FC | 0 : 2 | Chainat FC | H2H | Finished |
| 12:00 | FT | Bangkok FC | 0 : 5 | Ang Thong FC | H2H | Finished |
| 12:00 | FT | Prachuap FC | 7 : 2 | Samut Songkhram | H2H | Finished |
| 12:00 | FT | PTT Rayong FC | 1 : 0 | Lampang FC | H2H | Finished |
| 15:00 | FT | Kasba Tadla | 0 : 0 | Tihad Casablanca | Finished |
| 15:00 | FT | Riadi Salmi | 1 : 1 | FAR Rabat | Finished |
| 14:00 | FT | Chabab Rif Al Hoceima | 0 : 1 | AS Sale | Finished |
| 15:00 | FT | Olympique Khouribga | 2 : 0 | Rapide Oued Zem | Finished |
| 17:30 | FT | Orlando Pirates | 1 : 0 | FC Cape Town | H2H | Finished |
| 17:30 | FT | Polokwane City | 2 : 3 | Free State Stars | H2H | Finished |
| 17:30 | FT | SuperSport United | 1 : 1 | Chippa United | H2H | Finished |
| 17:30 | HT | AmaZulu | 1 : 0 | Bidvest Wits | H2H | Half Time |
| 17:30 | HT | Bloemfontein Celtic | 0 : 1 | Baroka | H2H | Half Time |
| 17:30 | HT | Maritzburg United | 0 : 1 | Kaizer Chiefs | H2H | Half Time |
| 17:30 | HT | Platinum Stars | 0 : 0 | Golden Arrows | H2H | Half Time |
| 00:00 | Pst | Monarcas Morelia | 0 : 0 | Tijuana | Postp. |
| 00:00 | Pst | Monterrey | 0 : 0 | Leones Negros Guadalajara | Postp. |
| 01:00 | Pst | Club America | 0 : 0 | Cruz Azul | Postp. |
| 02:35 | Pst | Guadalajara Chivas | 0 : 0 | Atlas | Postp. |
| 22:05 | FT | Gimnasia La Plata | 1 : 3 | CA Huracan | H2H | Finished |
| 00:05 | FT | Temperley | 1 : 1 | Rosario Central | H2H | Finished |
| 00:10 | FT | Independiente | 1 : 2 | Atletico Tucuman | Finished |
| 21:00 | - | Atlanta | - : - | Pacifico SC |
| 00:05 | FT | Sarmiento Junin | 0 : 0 | Quilmes AC | H2H | Finished |
| 22:15 | FT | America Mineiro | 1 : 0 | Vila Nova | H2H | Finished |
| 00:30 | FT | Guarani FC | 0 : 4 | Parana | H2H | Finished |
| 01:00 | FT | Atletico Bucaramanga | 1 : 1 | Independiente Medellin | H2H | Finished |
| 00:45 | - | Santos | - : - | Barcelona SC |
| 22:15 | FT | Estudiantes de La Plata | 0 : 1 | Nacional | Finished |
| 00:45 | FT | Junior Barranquilla | 3 : 1 | Cerro Porteno | Finished |
| 22:15 | - | Flamengo | - : - | Chapecoense |
| 23:10 | FT | Deportivo Capiata | 1 : 0 | Libertad Asuncion | H2H | Finished |
| 09:30 | FT | Australia (W) | 3 : 2 | Brazil (W) | Finished |
| 14:00 | FT | Portugal (W) | 1 : 1 | Finland (W) | Finished |
| 23:30 | FT | USA (W) | 5 : 0 | New Zealand (W) | Finished |
| 13:00 | FT | Cyprus U19 | 1 : 0 | Slovakia U19 | Finished |
| 08:00 | FT | Mexico U19 | 5 : 0 | Tajikistan U19 | Finished |
| 13:00 | FT | Czech Republic U17 | 1 : 0 | Montenegro U17 | Finished |
| 14:00 | FT | Bulgaria U17 | 2 : 5 | Turkey U17 | Finished |
| 14:00 | FT | Croatia U17 | 4 : 2 | Slovenia U17 | Finished |
| 14:00 | FT | Czech Republic U16 | 2 : 6 | France U16 | Finished |
| 09:30 | Pen | Blacktown City | 4 : 6 | Western Sydney | Pen: 2-4 |
| 09:30 | FT | Gold Coast City FC | 0 : 6 | South Melbourne | Finished |
- CUSTOMISE
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