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| 12:30 | FT | Stoke City | 1 : 1 | Burnley | H2H | Finished |
| 15:30 | FT | Manchester City | 5 : 0 | Swansea City | H2H | Finished |
| 14:00 | FT | Chelsea | 2 : 0 | Southampton | Finished |
| 14:15 | FT | Malaga CF | 2 : 0 | Real Sociedad | H2H | Finished |
| 16:30 | FT | Las Palmas | 0 : 4 | Deportivo Alaves | H2H | Finished |
| 18:45 | FT | Atletico Madrid | 0 : 0 | Real Betis | H2H | Finished |
| 13:00 | FT | Chievo Verona | 1 : 2 | Inter Milan | H2H | Finished |
| 13:30 | FT | FC Augsbourg | 2 : 0 | 1. FSV Mainz 05 | H2H | Finished |
| 16:00 | FT | 1. FC Koln | 2 : 2 | FC Schalke 04 | H2H | Finished |
| 13:00 | FT | Nice | 1 : 0 | Montpellier | H2H | Finished |
| 15:00 | FT | Saint-Etienne | 2 : 1 | ESTAC Troyes | H2H | Finished |
| 19:00 | FT | Bordeaux | 0 : 1 | Paris Saint Germain | H2H | Finished |
| 15:00 | FT | Chaves | 2 : 1 | Portimonense | H2H | Finished |
| 17:00 | FT | Moreirense | 2 : 1 | Rio Ave | H2H | Finished |
| 19:15 | FT | Sporting Lisbon | 1 : 0 | Boavista | H2H | Finished |
| 11:00 | FT | Arsenal Tula | 3 : 3 | Zenit St. Petersburg | H2H | Finished |
| 13:30 | FT | CSKA Moscow | 2 : 1 | FC Krasnodar | H2H | Finished |
| 13:30 | FT | FK Tosno | 0 : 2 | FC Amkar Perm | H2H | Finished |
| 16:00 | FT | Lokomotiv Moscow | 0 : 0 | FC Ufa | H2H | Finished |
| 17:00 | FT | Flamurtari Vlore | 3 : 1 | Teuta Durres | H2H | Finished |
| 14:00 | FT | Inter Club d'Escaldes | 3 : 1 | UE Santa Coloma | H2H | Finished |
| 16:00 | FT | Penya Encarnada | 2 : 1 | FC Encamp | H2H | Finished |
| 12:30 | FT | Red Bull Salzbourg | 3 : 1 | SCR Altach | H2H | Finished |
| 14:30 | FT | Rapid Wien | 4 : 1 | Admira Wacker | H2H | Finished |
| 15:00 | FT | Neftchi Baku | 1 : 0 | FK Gabala | H2H | Finished |
| 15:00 | FT | Sumgayit FK | 0 : 1 | Qarabag Agdam | H2H | Finished |
| 11:00 | FT | Torpedo Minsk | 0 : 1 | Neman Grodno | H2H | Finished |
| 14:00 | FT | Isloch Minsk | 0 : 0 | Gorodeya | H2H | Finished |
| 16:00 | FT | Dinamo Brest | 2 : 2 | Smolevichi-STI | H2H | Finished |
| 18:00 | FT | KV Oostende | 2 : 2 | Beerschot-Wilrijk | Finished |
| 16:00 | FT | Club Brugge | 4 : 4 | Standard Liege | Finished |
| 18:30 | FT | Sporting Charleroi | 2 : 1 | KAA Gent | Finished |
| 15:00 | FT | Sarajevo | 2 : 0 | Siroki Brijeg | Finished |
| 15:00 | FT | Sloboda Tuzla | 1 : 2 | Gosk Gabela | Finished |
| 14:30 | FT | Pirin Blagoevgrad | 2 : 2 | Vitosha Bistritsa | H2H | Finished |
| 17:00 | FT | Dunav Ruse | 1 : 0 | FC Etar | H2H | Finished |
| 14:00 | FT | Lokomotiv Gorna | 1 : 1 | Maritsa Plovdiv | H2H | Finished |
| 14:00 | FT | Pomorie | 1 : 1 | Neftohimik | H2H | Finished |
| 14:00 | FT | Strumska slava | 2 : 1 | Ludogorets Razgrad II | H2H | Finished |
| 15:00 | FT | FC Sozopol | 1 : 3 | Oborishte | H2H | Finished |
| 15:00 | FT | Litex Lovech | 0 : 0 | Lokomotiv Sofia | H2H | Finished |
| 15:00 | FT | Hajduk Split | 1 : 2 | Dinamo Zagreb | H2H | Finished |
| 17:30 | FT | Lokomotiva zagreb | 0 : 0 | NK Istra 1961 | H2H | Finished |
| 16:00 | FT | AEK Larnaca | 1 : 3 | Apoel FC | H2H | Finished |
| 16:00 | FT | Apollon Limassol | 3 : 1 | Anorthosis | H2H | Finished |
| 16:00 | FT | Slovan Liberec | 0 : 0 | Slavia Prague | H2H | Finished |
| 15:00 | FT | Ceske Budejovice | 4 : 1 | Banik Sokolov | H2H | Finished |
| 15:00 | FT | Graffin Vlasim | 2 : 2 | Opava | H2H | Finished |
| 15:00 | FT | Varnsdorf | 1 : 0 | Usti nad Labem | H2H | Finished |
| 12:00 | FT | Slavia Prague (W) | 4 : 0 | Viktoria Plzen (W) | H2H | Finished |
| 14:00 | FT | AaB Aalborg | 3 : 3 | FC Midtjylland | H2H | Finished |
| 18:00 | FT | FC Nordsjaelland | 3 : 4 | Brondby IF | H2H | Finished |
| 11:00 | FT | Hradec Kralove U21 | 2 : 1 | Banik Ostrava U21 | H2H | Finished |
| 11:00 | FT | Mlada Boleslav U21 | 1 : 3 | Slovacko U21 | H2H | Finished |
| 11:00 | FT | Jablonec U21 | 3 : 3 | Brno U21 | Finished |
| 12:00 | FT | Fortuna Hjorring (W) | 1 : 0 | BSF (W) | Finished |
| 11:00 | FT | Avarta | 0 : 2 | Hvidovre IF | H2H | Finished |
| 12:00 | FT | Ringkobing IF | 3 : 0 | BK Marienlyst | H2H | Finished |
| 11:30 | FT | Reading FC (W) | 3 : 0 | Everton LFC (W) | H2H | Finished |
| 13:00 | Pst | Chelsea LFC (W) | 0 : 0 | Birmingham LFC (W) | H2H | Postp. |
| 12:00 | FT | Paide Linnameeskond | 1 : 3 | FC Levadia Tallinn | H2H | Finished |
| 16:00 | FT | Flora Tallinn II | 1 : 0 | Tallinna Kalev II | H2H | Finished |
| 13:00 | FT | IFK Mariehamn | 2 : 2 | VPS Vaasa | H2H | Finished |
| 12:00 | FT | Manchester City (W) | 0 : 0 | Lyon (W) | Finished |
| 17:05 | FT | Chelsea LFC (W) | 1 : 3 | VfL Wolfsburg (W) | Finished |
| 12:00 | FT | Lille (W) | 1 : 0 | Guingamp (W) | Finished |
| 13:00 | FT | ASPTT Albi (W) | 1 : 1 | Rodez Aveyron (W) | Finished |
| 13:00 | FT | Girondins Bordeaux (W) | 0 : 0 | Montpellier (W) | Finished |
| 13:00 | FT | Soyaux (W) | 1 : 1 | Paris FC (W) | Finished |
| 14:30 | FT | Paris Saint-Germain (W) | 4 : 0 | Olympique Marseille (W) | Finished |
| 12:00 | FT | Chikhura Sachkhere | 0 : 0 | Samtredia | H2H | Finished |
| 16:00 | FT | Saburtalo Tbilisi | 2 : 0 | Torpedo Kutaisi | H2H | Finished |
| 11:30 | FT | FC Erzgebirge Aue | 1 : 3 | MSV Duisbourg | H2H | Finished |
| 11:30 | FT | FC Kaiserslautern | 0 : 1 | SG Dynamo Dresden | H2H | Finished |
| 11:30 | FT | SC Fortuna Dusseldorf | 3 : 0 | FC Ingolstadt | H2H | Finished |
| 12:00 | FT | SC Preussen Munster | 1 : 2 | Hallescher FC | H2H | Finished |
| 12:00 | FT | VfR Aalen | 2 : 1 | VfL Osnabruck | H2H | Finished |
| 12:00 | FT | FC Bayern Munich (W) | 0 : 0 | USV Jena W | H2H | Finished |
| 12:00 | FT | SGS Essen (W) | 3 : 1 | FCR Duisburg (W) | H2H | Finished |
| 12:00 | FT | TSG 1899 Hoffenheim (W) | 0 : 1 | SC Freiburg (W) | H2H | Finished |
| 16:00 | FT | AEK Athens | 2 : 0 | Levadiakos | H2H | Finished |
| 16:00 | FT | AOK Kerkyra | 1 : 3 | Asteras Tripolis | H2H | Finished |
| 16:00 | FT | Apollon Smyrni | 1 : 0 | Olympiakos | H2H | Finished |
| 16:00 | FT | Panaitolikos | 1 : 0 | Lamia FC | H2H | Finished |
| 16:00 | FT | Panionios | 0 : 3 | Panathinaikos | H2H | Finished |
| 16:00 | FT | PAOK Salonika | 2 : 1 | Xanthi | H2H | Finished |
| 16:00 | FT | PAS Giannina | 0 : 0 | AEL Larissa | H2H | Finished |
| 14:00 | FT | Aiginiakos | 2 : 0 | Sparta FC | H2H | Finished |
| 14:00 | FT | Anagennisi Karditsas | 1 : 0 | Panserraikos | H2H | Finished |
| 14:00 | FT | Apollon Kalamarias | 0 : 0 | Aris Thessaloniki | H2H | Finished |
| 14:00 | FT | Apollon Larissa | 0 : 1 | Panachaiki | H2H | Finished |
| 14:00 | FT | Ergotelis | 4 : 1 | Karaiskakis | H2H | Finished |
| 14:00 | FT | Panegialios | 1 : 0 | Doxa Dramas | H2H | Finished |
| 15:00 | FT | Budaorsi SC | 1 : 1 | Kisvarda FC | H2H | Finished |
| 15:00 | FT | Dorogi FC | 1 : 0 | Gyori ETO FC | H2H | Finished |
| 15:00 | FT | Gyirmot | 2 : 2 | Bekescsaba | H2H | Finished |
| 15:00 | FT | Kazincbarcikai SC | 1 : 0 | Soproni VSE | H2H | Finished |
| 15:00 | FT | Nyiregyhaza Spartacus | 0 : 0 | Zalaegerszeg TE | H2H | Finished |
| 15:00 | FT | Soroksar | 0 : 0 | Mosonmagyarovari | H2H | Finished |
| 15:00 | FT | Szeged 2011 FC | 2 : 2 | MTK Budapest | H2H | Finished |
| 15:00 | FT | Szolnoki MAV | 2 : 4 | Aqvital FC Csakvar | H2H | Finished |
| 15:00 | FT | Vac FC | 1 : 1 | Cegledi VSE | H2H | Finished |
| 11:00 | FT | Durham WFC | 2 : 1 | Millwall Lionesses LFC (W) | H2H | Finished |
| 12:00 | FT | Tottenham LFC | 2 : 4 | Sheffield FC (W) | H2H | Finished |
| 13:00 | FT | Aston Villa LFC (W) | 1 : 0 | Oxford United (W) | H2H | Finished |
| 14:00 | FT | Watford LFC (W) | 0 : 4 | London Bees (W) | H2H | Finished |
| 17:30 | FT | Maccabi Netanya FC | 1 : 5 | Hapoel Beer Sheva FC | H2H | Finished |
| 13:00 | FT | Perugia | 2 : 3 | Ternana Calcio | H2H | Finished |
| 15:30 | FT | Pescara | 3 : 2 | Spezia Calcio | H2H | Finished |
| 14:30 | FT | Bassano Virtus | 0 : 1 | Gubbio | H2H | Finished |
| 14:30 | FT | Fermana | 1 : 1 | Calcio Padova | H2H | Finished |
| 14:30 | FT | Pordenone | 4 : 0 | Sambenedettese | H2H | Finished |
| 14:30 | FT | Ravenna Calcio | 2 : 0 | Vicenza Calcio | H2H | Finished |
| 14:30 | FT | Santarcangelo | 0 : 1 | Renate | H2H | Finished |
| 14:30 | FT | Sudtirol | 3 : 2 | AC FeralpiSalo | H2H | Finished |
| 12:30 | Pst | Cosenza Calcio | 0 : 3 | Rende | H2H | Postp. |
| 12:30 | FT | Paganese | 1 : 2 | Sicula Leonzio | H2H | Finished |
| 12:30 | FT | Siracusa | 1 : 1 | AS Bisceglie | H2H | Finished |
| 14:30 | FT | Casertana | 3 : 1 | Juve Stabia | H2H | Finished |
| 16:30 | FT | Fidelis Andria | 0 : 1 | Matera | H2H | Finished |
| 16:30 | FT | Monopoli | 1 : 1 | Francavilla | H2H | Finished |
| 12:00 | FT | Spartaks Jurmala | 1 : 2 | FK Ventspils | H2H | Finished |
| 12:00 | FT | JDFS Alberts | 3 : 2 | Grobinas SC | H2H | Finished |
| 13:00 | FT | Utenis Utena | 6 : 1 | Kupiskis | H2H | Finished |
| 15:00 | FT | Vilniaus Vytis | 2 : 1 | FK Dziugas Telsiai | H2H | Finished |
| 14:00 | FT | Differdange | 0 : 2 | Petange | H2H | Finished |
| 14:00 | FT | Dudelange | 3 : 2 | UNA Strassen | H2H | Finished |
| 14:00 | FT | FC Rodange 91 | 1 : 1 | Rosport | H2H | Finished |
| 14:00 | FT | Jeunesse Esch | 1 : 2 | Racing FC Union | H2H | Finished |
| 14:00 | FT | Mondorf-les-Bains | 0 : 1 | Fola Esch | H2H | Finished |
| 14:00 | FT | RM Hamm Benfica | 1 : 2 | Progres Niedercorn | H2H | Finished |
| 14:00 | FT | Pieta Hotspurs | 4 : 2 | Zejtun Corinthians | H2H | Finished |
| 14:00 | FT | San Gwann FC | 1 : 2 | Qormi FC | H2H | Finished |
| 16:15 | FT | Qrendi FC | 5 : 0 | Vittoriosa Stars | H2H | Finished |
| 16:15 | FT | Zabbar St. Patrick | 1 : 3 | Zebbug Rangers | H2H | Finished |
| 13:00 | FT | FC Milsami | 1 : 0 | Sfintul Gheorghe | H2H | Finished |
| 13:00 | FT | FC Petrocub | 3 : 0 | Zaria Balti | H2H | Finished |
| 15:00 | FT | Sheriff Tiraspol | 5 : 2 | Dinamo-Auto | H2H | Finished |
| 15:00 | FT | Zimbru Chisinau | 1 : 1 | Speranta | H2H | Finished |
| 16:00 | FT | Feyenoord | 3 : 0 | AZ Alkmaar | Finished |
| 13:00 | FT | Virtus Entella U19 | 0 : 0 | Cremonese U19 | H2H | Finished |
| 13:00 | FT | Strommen IF | 3 : 0 | Levanger FK | H2H | Finished |
| 16:00 | FT | Aalesunds FK | 4 : 0 | Tromsdalen UIL | H2H | Finished |
| 16:00 | FT | FK Jerv | 0 : 0 | Mjondalen IF | H2H | Finished |
| 16:00 | FT | Floro SK | 1 : 4 | Notodden FK | H2H | Finished |
| 16:00 | FT | Nest-Sotra | 0 : 3 | Ullensaker Kisa | H2H | Finished |
| 16:00 | FT | Sogndal | 4 : 1 | Kongsvinger | H2H | Finished |
| 16:00 | FT | FK Haugesund | 1 : 0 | Stromsgodset IF | H2H | Finished |
| 16:00 | FT | Kristiansund BK | 1 : 1 | Bodo/Glimt | H2H | Finished |
| 16:00 | FT | Lillestrom | 0 : 1 | Ranheim | H2H | Finished |
| 16:00 | FT | Tromso | 4 : 1 | Sandefjord | H2H | Finished |
| 10:30 | FT | Klepp IL (W) | 6 : 0 | Grand Bodo (W) | H2H | Finished |
| 13:00 | FT | Avaldsnes (W) | 0 : 3 | Valerenga (W) | H2H | Finished |
| 12:00 | FT | Alta IF | 2 : 1 | Honefoss BK | H2H | Finished |
| 14:00 | FT | Asker | 5 : 1 | FK Mjolner | H2H | Finished |
| 14:00 | FT | Nybergsund | 0 : 5 | Raufoss | H2H | Finished |
| 14:00 | FT | Stabaek II | 1 : 2 | Fram Larvik | H2H | Finished |
| 12:00 | FT | Arendal | 2 : 3 | Stjordals-Blink | H2H | Finished |
| 16:00 | FT | Egersunds IK | 0 : 0 | Bryne FK | H2H | Finished |
| 13:30 | FT | Wigry Suwalki | 1 : 0 | Zaglebie Sosnowiec | H2H | Finished |
| 16:00 | FT | Wisla Krakow | 0 : 1 | Legia Warszaw | H2H | Finished |
| 13:30 | FT | Sandecja Nowy Sacz | 3 : 1 | Arka Gdynia | H2H | Finished |
| 13:00 | FT | Garbarnia Krakow | 2 : 1 | Blekitni Stargard | H2H | Finished |
| 14:00 | FT | Rozwoj Katowice | 2 : 1 | MKS Kluczbork | H2H | Finished |
| 15:00 | FT | Braga B | 2 : 2 | Academica Viseu | H2H | Finished |
| 15:00 | FT | Cova Piedade | 1 : 1 | Varzim | H2H | Finished |
| 15:00 | FT | Penafiel | 1 : 0 | Oliveirense | H2H | Finished |
| 15:00 | FT | Santa Clara | 2 : 0 | Famalicao | H2H | Finished |
| 13:00 | FT | FK Rabotnicki | 4 : 0 | Pelister Bitola | H2H | Finished |
| 14:00 | FT | FK Skopje | 0 : 2 | Academy Pandev | H2H | Finished |
| 14:00 | FT | Pobeda Prilep | 2 : 0 | Vardar | H2H | Finished |
| 14:00 | FT | Shkendija | 2 : 0 | Shkupi Skopje | H2H | Finished |
| 17:45 | FT | CSMS Politehnica Iasi | 1 : 1 | CFR Cluj | H2H | Finished |
| 15:00 | FT | Juventus Bucuresti | 0 : 3 | Gaz Metan Medias | H2H | Finished |
| 10:30 | FT | FK Tambov | 3 : 1 | Shinnik Yaroslavl | H2H | Finished |
| 14:00 | FT | Kuban Krasnodar | 0 : 3 | Avangard Kursk | H2H | Finished |
| 13:00 | FT | FK Strogino | 2 : 4 | Energomash | H2H | Finished |
| 15:10 | FT | Alloa Athletic | 2 : 1 | Ayr United | H2H | Finished |
| 11:30 | FT | Glasgow Rangers | 2 : 1 | Hearts | H2H | Finished |
| 12:00 | FT | Sportul Snagov | 1 : 2 | FC Chindia Targoviste | H2H | Finished |
| 16:00 | FT | Vojvodina | 0 : 2 | Spartak Subotica | H2H | Finished |
| 15:00 | FT | Backa Palanka | 1 : 1 | FK Macva Sabac | H2H | Finished |
| 15:00 | FT | Borac Cacak | 0 : 2 | Mladost Lucani | H2H | Finished |
| 11:00 | FT | NK Triglav Kranj | 2 : 2 | Ankaran Hrvatini | H2H | Finished |
| 14:50 | FT | NK Celje | 1 : 1 | Olimpija Ljubljana | H2H | Finished |
| 17:00 | FT | NK Domzale | 3 : 0 | NK Rudar Velenje | H2H | Finished |
| 15:00 | FT | NK Fuzinar | 2 : 4 | Brezice | H2H | Finished |
| 15:00 | FT | NS Mura | 3 : 0 | Jadran Dekani | H2H | Finished |
| 14:00 | FT | Barcelona B | 2 : 3 | Rayo Vallecano | H2H | Finished |
| 16:00 | FT | Cadiz CF | 0 : 0 | Sporting Gijon | H2H | Finished |
| 18:00 | FT | Granada CF | 3 : 3 | Cultural Leonesa | H2H | Finished |
| 15:00 | FT | Racing Ferrol | 4 : 1 | UD Sanse | H2H | Finished |
| 16:00 | FT | Guijuelo | 0 : 0 | Gimnastica Segoviana | H2H | Finished |
| 16:00 | FT | SD Ponferradina | 2 : 2 | Rapido de Bouzas | H2H | Finished |
| 17:00 | FT | Talavera CF | 2 : 0 | Atletico Madrid B | H2H | Finished |
| 18:00 | FT | Real Madrid Castilla | 1 : 1 | CF Fuenlabrada | H2H | Finished |
| 15:00 | FT | Burgos | 1 : 0 | CD Vitoria | H2H | Finished |
| 15:00 | FT | Caudal Deportivo | 1 : 2 | Athletic Bilbao B | H2H | Finished |
| 15:00 | FT | CD Tudelano | 0 : 0 | Racing Santander | H2H | Finished |
| 15:00 | FT | Real Union | 5 : 4 | Gernika | H2H | Finished |
| 16:00 | FT | Osasuna B | 0 : 0 | Pena Sport | H2H | Finished |
| 16:00 | FT | UD Logrones | 1 : 2 | Sporting Gijon B | H2H | Finished |
| 15:00 | FT | Ontinyent CF | 1 : 0 | Atletico Saguntino | H2H | Finished |
| 16:00 | FT | Villarreal B | 0 : 0 | CF Badalona | H2H | Finished |
| 15:00 | FT | Extremadura | 0 : 1 | CF Villanovense | H2H | Finished |
| 16:00 | FT | CD Badajoz | 2 : 3 | Real Murcia | H2H | Finished |
| 16:00 | FT | Recreativo Huelva | 2 : 1 | San Fernando CD | H2H | Finished |
| 11:00 | FT | FC Barcelona (W) | 5 : 0 | Sevilla FC (W) | H2H | Finished |
| 14:00 | FT | Madrid CFF (W) | 0 : 1 | Real Betis (W) | H2H | Finished |
| 13:00 | FT | Jonkopings Sodra | 0 : 1 | Oster IF | H2H | Finished |
| 15:30 | FT | Falkenbergs FF | 3 : 1 | IK Frej | H2H | Finished |
| 13:00 | FT | BK Hacken | 2 : 2 | Hammarby IF | H2H | Finished |
| 13:00 | FT | Dalkurd FF | 2 : 2 | GIF Sundsvall | H2H | Finished |
| 15:30 | FT | AIK Fotboll | 2 : 0 | IFK Goteborg | H2H | Finished |
| 15:30 | FT | Trelleborgs FF | 0 : 1 | Kalmar FF | H2H | Finished |
| 13:20 | FT | MSK Zilina | 2 : 3 | Dunajska Streda | H2H | Finished |
| 15:00 | FT | As Trencin | 1 : 3 | Slovan Bratislava | H2H | Finished |
| 13:00 | FT | Vittsjo GIK (W) | 3 : 2 | Linkoping (W) | H2H | Finished |
| 14:00 | FT | Eskilstuna United (W) | 1 : 2 | Pitea IF (W) | H2H | Finished |
| 14:00 | FT | Akropolis IF | 1 : 1 | Nykoping | H2H | Finished |
| 14:00 | FT | Sollentuna FK | 1 : 2 | Team ThorenGruppen | H2H | Finished |
| 14:00 | FT | Syrianska | 2 : 2 | BK Forward | H2H | Finished |
| 14:00 | FT | Young Boys | 4 : 1 | Lausanne-Sport | H2H | Finished |
| 14:00 | FT | Schaffhausen | 2 : 4 | Rapperswil-Jona | H2H | Finished |
| 14:00 | FT | Winterthur | 0 : 3 | Wil | H2H | Finished |
| 13:00 | FT | Akhisar Belediyespor | 1 : 1 | Goztepe | H2H | Finished |
| 16:00 | FT | Besiktas | 3 : 1 | Yeni Malatyaspor | H2H | Finished |
| 12:30 | FT | Adana Demirspor | 2 : 3 | BB Erzurumspor | H2H | Finished |
| 12:30 | FT | MKE Ankaragucu | 4 : 0 | Gaziantep FK | H2H | Finished |
| 15:00 | FT | Balikesirspor | 1 : 1 | Umraniyespor | H2H | Finished |
| 15:00 | FT | Rizespor | 1 : 0 | Giresunspor | H2H | Finished |
| 15:00 | FT | FC Trollhattan | 3 : 1 | Torslanda | H2H | Finished |
| 11:00 | FT | IFK Lidingo | 3 : 0 | Skiljebo SK | H2H | Finished |
| 12:00 | FT | Varmbols FC | 1 : 1 | Motala | H2H | Finished |
| 12:00 | FT | Hogaborgs BK | 4 : 2 | Varbergs GIF | H2H | Finished |
| 12:30 | FT | Afjet Afyonspor | 4 : 0 | Kastamonuspor | H2H | Finished |
| 12:30 | FT | Bodrumspor | 2 : 1 | Etimesgut Belediyespor | H2H | Finished |
| 12:30 | FT | Bucaspor | 1 : 1 | Menemen Belediyespor | H2H | Finished |
| 12:30 | FT | Hatayspor | 1 : 1 | Sancaktepespor | H2H | Finished |
| 12:30 | FT | Keciorengucu | 0 : 0 | Amed SK | H2H | Finished |
| 12:30 | FT | Mersin Idman Yurdu | 1 : 2 | Sariyer SK | H2H | Finished |
| 12:30 | FT | Sivas Belediyespor | 4 : 2 | Kocaeli BirlikSpor | H2H | Finished |
| 12:30 | FT | Tokatspor | 1 : 2 | Inegolspor | H2H | Finished |
| 12:30 | FT | Altay Izmir | 3 : 1 | Hacettepe SK | H2H | Finished |
| 12:30 | FT | Anadolu Selcuksport | 3 : 0 | Karsiyaka | H2H | Finished |
| 12:30 | FT | Fethiyespor | 0 : 1 | Bandirmaspor | H2H | Finished |
| 12:30 | FT | Karagumruk | 2 : 2 | BugsasSpor | H2H | Finished |
| 12:30 | FT | Kirklarelispor | 2 : 2 | Silivrispor | H2H | Finished |
| 12:30 | FT | Nazilli Belediyespor | 1 : 0 | Pendikspor | H2H | Finished |
| 12:30 | FT | Nigde Belediyespor | 0 : 0 | Sakaryaspor | H2H | Finished |
| 12:30 | FT | Sanliurfaspor | 1 : 1 | Gumushanespor | H2H | Finished |
| 12:30 | FT | Zonguldak Komurspor | 0 : 0 | Kahramanmarasspor | H2H | Finished |
| 11:00 | FT | FC Sumy | 0 : 2 | Desna Chernihiv | H2H | Finished |
| 13:00 | FT | Arsenal Kiev | 2 : 0 | Zhemchuzhyna Odesa | H2H | Finished |
| 13:00 | FT | Cherkaskyi Dnipro | 2 : 1 | Avanhard Kramatorsk | H2H | Finished |
| 13:00 | FT | Kremin Kremenchuk | 2 : 0 | Hirnyk-Sport Komsomolsk | H2H | Finished |
| 13:30 | FT | Naftovyk-Ukrnafta | 1 : 1 | Balkany Zorya | H2H | Finished |
| 15:00 | FT | Inhulets Petrove | 1 : 0 | Volyn Lutsk | H2H | Finished |
| 14:00 | FT | Bangor City | 1 : 0 | Cefn Druids | H2H | Finished |
| 11:00 | FT | Olimpik Donetsk | 0 : 2 | Karpaty Lviv | H2H | Finished |
| 11:00 | FT | Zorya Luhansk | 3 : 1 | Illichivets Mariupol | H2H | Finished |
| 14:00 | FT | Veres Rivne | 1 : 4 | Dynamo Kiev | H2H | Finished |
| 11:35 | FT | Beijing Guoan | 2 : 2 | Guangzhou Evergrande | H2H | Finished |
| 12:00 | FT | Shanghai SIPG | 1 : 1 | Tianjin Teda | H2H | Finished |
| 11:30 | FT | Meizhou Meixian Techand | 4 : 2 | Zhejiang Yiteng | H2H | Finished |
| 11:30 | FT | Shijiazhuang Ever Bright | 2 : 2 | Liaoning FC | H2H | Finished |
| 11:30 | FT | Wuhan Zall | 3 : 0 | Xinjiang Tianshan Leopard | H2H | Finished |
| 11:35 | FT | Zhejiang Greentown | 1 : 1 | Shenzhen FC | H2H | Finished |
| 11:30 | FT | Persebaya Surabaya | 1 : 1 | Sriwijaya FC | H2H | Finished |
| 13:30 | FT | Esteghlal Khuzestan | 3 : 2 | Mobarake Sepahan | H2H | Finished |
| 13:30 | FT | Padideh FC | 2 : 1 | Siah Jamegan | H2H | Finished |
| 13:30 | FT | Pars Jonoubi Jam | 3 : 0 | Naft Tehran | H2H | Finished |
| 13:30 | FT | Saipa FC | 0 : 0 | Gostaresh Folad | H2H | Finished |
| 13:30 | FT | Sepidrood Rasht | 0 : 0 | Foolad Khuzestan | H2H | Finished |
| 13:30 | FT | Tractor Sazi | 1 : 1 | Sanat Naft | H2H | Finished |
| 13:30 | FT | Zob Ahan | 2 : 1 | Persepolis Tehran | H2H | Finished |
| 11:00 | FT | Kairat Almaty | 4 : 1 | Kaisar Kyzylorda | H2H | Finished |
| 11:00 | FT | Chiangrai United | 1 : 0 | Buriram United | H2H | Finished |
| 11:00 | FT | Police Tero FC | 2 : 1 | Sukhothai FC | H2H | Finished |
| 12:00 | FT | Nakhon Ratchasima | 2 : 0 | Pattaya United | H2H | Finished |
| 12:00 | FT | Suphanburi FC | 2 : 2 | Ratchaburi FC | H2H | Finished |
| 11:00 | FT | PTT Rayong FC | 2 : 2 | Lampang FC | H2H | Finished |
| 12:00 | FT | Chiangmai FC | 2 : 1 | Kasetsart FC | H2H | Finished |
| 12:00 | FT | Krabi FC | 0 : 0 | Nong Bua Pitchaya | H2H | Finished |
| 11:00 | FT | Ho Chi Minh City | 0 : 1 | Hai Phong | H2H | Finished |
| 13:30 | FT | El Raja | 0 : 0 | Ismaily SC | H2H | Finished |
| 15:45 | FT | Petrojet FC | 1 : 2 | Al Ahly Cairo | H2H | Finished |
| 18:00 | FT | Zamalek | 2 : 1 | Alassiouty Sport | H2H | Finished |
| 15:00 | FT | Difaa El Jadida | 2 : 1 | Raja Casablanca | H2H | Finished |
| 15:00 | FT | FUS Rabat | 2 : 1 | Hassania Agadir | H2H | Finished |
| 15:00 | FT | RSB Berkane | 2 : 3 | FAR Rabat | H2H | Finished |
| 17:00 | FT | Moghreb Tetouan | 2 : 1 | Olympique Khouribga | H2H | Finished |
| 13:00 | FT | Bidvest Wits | 1 : 1 | Polokwane City | H2H | Finished |
| 13:00 | FT | CA Bizertin | 1 : 1 | Club Africain | Finished |
| 13:00 | FT | Etoile du Sahel | 1 : 0 | AS Gabes | Finished |
| 13:00 | FT | Maritzburg United | 3 : 1 | Mamelodi Sundowns | Finished |
| 21:00 | FT | Santos Guapiles | 0 : 1 | CS Herediano | Finished |
| 23:00 | 20' | LD Alajuelense | 0 : 0 | Deportivo Saprissa | 1st Half |
| 21:15 | FT | CD Audaz | 2 : 1 | Luis Angel Firpo | H2H | Finished |
| 21:15 | FT | Isidro Metapan | 2 : 1 | Chalatenango | H2H | Finished |
| 21:15 | FT | Municipal Limeno | 1 : 2 | Santa Tecla | H2H | Finished |
| 17:00 | FT | Deportivo Sanarate | 1 : 1 | Guastatoya | H2H | Finished |
| 21:45 | 83' | Suchitepequez | 0 : 0 | CSD Municipal | H2H | 2nd Half |
| 22:00 | 60' | CD Olimpia | 2 : 0 | Platense FC | 2nd Half |
| 23:00 | 22' | Santos Laguna | 0 : 1 | Pumas UNAM | H2H | 1st Half |
| 17:00 | FT | Leones Negros Guadalajara | 1 : 1 | Alebrijes De Oaxaca | Finished |
| 21:00 | FT | Orlando Pride (W) | 1 : 0 | Houston Dash (W) | H2H | Finished |
| 14:00 | FT | CA Tigre | 0 : 2 | CA Huracan | H2H | Finished |
| 16:15 | FT | Rosario Central | 0 : 2 | Racing Club | H2H | Finished |
| 18:30 | FT | Atletico Tucuman | 0 : 0 | Union Santa Fe | H2H | Finished |
| 20:45 | FT | Arsenal Sarandi | 0 : 3 | River Plate | H2H | Finished |
| 23:00 | 27' | Boca Juniors | 0 : 0 | Newells Old Boys | H2H | 1st Half |
| 18:30 | FT | Villa Dalmine | 3 : 0 | Deportivo Moron | H2H | Finished |
| 19:00 | Pst | Club Sportivo Estudiantes | 0 : 0 | Rivadavia | H2H | Postp. |
| 20:00 | FT | Gimnasia Jujuy | 0 : 0 | CA Mitre | H2H | Finished |
| 20:00 | FT | Quilmes AC | 1 : 1 | Boca Unidos | H2H | Finished |
| 21:30 | 90' | Instituto AC Cordoba | 1 : 1 | Club Agropecuario | H2H | 2nd Half |
| 20:00 | FT | Seattle Sounders | 3 : 1 | Minnesota United | H2H | Finished |
| 22:00 | 53' | Portland Timbers | 2 : 0 | New York City | H2H | 2nd Half |
| 17:35 | FT | Acassuso | 1 : 2 | Estudiantes de Caseros | H2H | Finished |
| 18:30 | FT | Comunicaciones | 1 : 2 | Atlanta | H2H | Finished |
| 18:30 | FT | Sacachispas FC | 2 : 2 | Tristan Suarez | H2H | Finished |
| 19:00 | Ssp | Jorge Wilstermann | 7 : 0 | Universitario Sucre | H2H | Suspended |
| 19:00 | FT | Nacional Potosi | 4 : 3 | Blooming | H2H | Finished |
| 14:00 | FT | Parana | 0 : 4 | Corinthians | H2H | Finished |
| 19:00 | FT | Atletico Mineiro (MG) | 2 : 1 | EC Vitoria | H2H | Finished |
| 19:00 | FT | Chapecoense | 1 : 1 | Vasco da Gama | H2H | Finished |
| 19:00 | FT | Fluminense | 1 : 0 | Cruzeiro | H2H | Finished |
| 19:00 | FT | Palmeiras | 1 : 0 | Internacional | H2H | Finished |
| 22:00 | 65' | Gremio | 0 : 0 | Atletico PR | H2H | 2nd Half |
| 18:00 | FT | FC Ypiranga | 2 : 1 | Operario Ferroviario | H2H | Finished |
| 19:00 | FT | ABC Natal | 1 : 0 | Juazeirense | H2H | Finished |
| 22:00 | FT | Santa Cruz | 3 : 1 | Atletico Acreano | H2H | Finished |
| 19:00 | FT | Envigado | 0 : 3 | Atletico Huila | H2H | Finished |
| 21:00 | FT | Jaguares De Cordoba | 1 : 0 | Deportivo Cali | H2H | Finished |
| 22:15 | 52' | America de Cali | 2 : 0 | Junior Barranquilla | H2H | 2nd Half |
| 23:00 | 27' | Alianza Petrolera | 1 : 0 | Rionegro Aguilas | H2H | 1st Half |
| 17:00 | FT | Deportivo Macara | 0 : 1 | LDU Quito | H2H | Finished |
| 22:30 | HT | Barcelona SC | 1 : 0 | Deportivo Cuenca | H2H | Half Time |
| 14:00 | FT | Atenas | 3 : 1 | Atletico Fenix | H2H | Finished |
| 19:00 | FT | Boston River | 3 : 2 | Atletico Progreso | H2H | Finished |
| 19:00 | FT | Penarol | 1 : 1 | Nacional Montevideo | H2H | Finished |
| 19:00 | Pst | Puerto Cabello | 0 : 0 | Monagas SC | H2H | Postp. |
| 19:30 | FT | Metropolitanos | 1 : 0 | Atletico Venezuela | H2H | Finished |
| 20:00 | FT | Estudiantes de Merida | 2 : 1 | Deportivo Tachira | H2H | Finished |
| 23:00 | 25' | Portuguesa FC | 0 : 0 | Zamora FC | H2H | 1st Half |
| 15:00 | FT | O Higgins | 2 : 2 | Curico Unido | H2H | Finished |
| 18:00 | FT | Union La Calera | 6 : 1 | Universidad de Chile | H2H | Finished |
| 20:30 | FT | Universidad Catolica | 1 : 0 | Audax Italiano | H2H | Finished |
| 23:00 | 26' | CD Antofagasta | 1 : 0 | San Luis de Quillota | H2H | 1st Half |
| 18:30 | FT | Comerciantes Unidos | 1 : 2 | UTC Cajamarca | H2H | Finished |
| 21:00 | FT | Alianza Lima | 3 : 1 | Sport Rosario | H2H | Finished |