| 15:30 | 2T | Nations 2 : 1 Medeama SC | H2H |
| 02.14.26 15:00 | Medeama SC - : - Aduana Stars |
| 05.23.26 15:00 | Hearts of Oak SC - : - Medeama SC |
| 05.16.26 15:00 | Medeama SC - : - Hearts of Lions |
| 05.15.26 15:00 | Medeama SC - : - Accra Lions |
| 05.09.26 15:00 | Basake Holy Stars - : - Medeama SC |
| 05.02.26 15:00 | Medeama SC - : - Bibiani Gold Stars |
| 04.25.26 15:00 | Berekum Chelsea - : - Medeama SC |
| 04.11.26 15:00 | Medeama SC - : - Asante Kotoko |
| 04.04.26 15:00 | Bechem United - : - Medeama SC |
| 03.28.26 16:00 | Medeama SC - : - Eleven Wonders FC |
| 03.21.26 16:00 | Dreams FC - : - Medeama SC |
| 03.07.26 16:00 | Medeama SC - : - Hohoe United |
| 02.22.26 15:00 | Samartex - : - Medeama SC |
| 02.14.26 15:00 | Medeama SC - : - Aduana Stars |
| 12.26.25 15:00 | Accra Lions - : - Medeama SC |
| 01.25.26 15:00 | Medeama SC 3 : 1 Karela FC |
| 01.17.26 15:00 | Vision FC 1 : 2 Medeama SC |
| 01.11.26 15:00 | Medeama SC 3 : 0 Young Apostles |
| 01.04.26 15:30 | Medeama SC 1 : 0 Hearts of Oak SC |
| 12.31.25 15:00 | Bibiani Gold Stars 0 : 0 Medeama SC |
| 12.27.25 15:30 | Hearts of Lions 0 : 1 Medeama SC |
| 12.22.25 16:00 | Medeama SC 1 : 1 Basake Holy Stars |
| 12.07.25 15:00 | Medeama SC 2 : 1 Berekum Chelsea |
| 11.30.25 16:00 | Asante Kotoko 2 : 2 Medeama SC |
| 11.22.25 15:30 | Medeama SC 0 : 0 Bechem United |
| 11.16.25 15:00 | Eleven Wonders FC 1 : 2 Medeama SC |
| 11.08.25 15:30 | Aduana Stars 0 : 0 Medeama SC |
| 11.01.25 15:30 | Hohoe United 1 : 1 Medeama SC |
| 10.18.25 15:00 | Medeama SC 1 : 1 Samartex |
| 10.10.25 16:30 | Medeama SC 2 : 1 Dreams FC |
| 10.05.25 15:00 | Medeama SC 2 : 1 Nations |
| 09.28.25 15:00 | Karela FC 1 : 0 Medeama SC |
| 09.19.25 17:00 | Medeama SC 4 : 0 Vision FC |
| 09.14.25 15:00 | Young Apostles 0 : 2 Medeama SC |
| 08.30.25 15:30 | Dreams FC 4 : 2 Medeama SC |
Clubs | P | Pts |
1 | Medeama SC | 21 | 43 |